To add to what I wrote above...

...I've grown so bored with facing teams that plop down in the same blob of hindering on the great arena map that reluctantly built a HSS/TK team (with gobs of PC) because many of the pieces that favor that strategy can be KOed with 5 or 6 clicks of damage (so I don't need to fret about support from Ghost Widow, or Nanobots) or are less threatening 3/4 clicks into their dial.

My own experiences with/against Spies:

Iron Widow: always has trouble actually HITTING figures, and is only really threatening while she has move+attack. If opponents go after her first I usually can win...when I face her I try to save her for last.

Winter Soldier: Very threatening on the top clicks, but a solid hit quickly reduces his effectiveness.

Most other spies can be KO-ed with a single shot from most HSS+SS figures.