Crimson Gem of Cyttorak
This object can't be destroyed.
Once per game per character, give a character occupying this square a power action and roll a d6 that can't be rerolled. On a 5 or 6, place this object on that character's card. Modify that character's damage value by +1 and that character can use Charge, Super Strength, and Toughness. (Characters can't use more than 1 damage reduction power.) When that character is defeated, place this object in the square they last occupied. At the end of the game, if an opponent's character has this object on their card or all of your characters have been defeated, your opponent scores this object.

Tried a search and didn't find an answer to this.

I know you can't stack the reduction as per the bolded portion above, but would the toughness granted from the gem come into play if the figure's main damage reduction power is outwitted?

Thanks.

Yes it would.

The question was answered, but I felt it should be added: You get to choose which reducer you use. This won't matter much unless you are quite good at memorizing dials. If you know what click is the sweet spot, you might be able to choose Toughness instead of Invulnerable and get to a click number that might work better for the game.