I should just stop reading here. Best answer imaginable.

Doom is the only one worthy of the gauntlet!

Seriously, I played GG normal Dr Doom with SI Mr F and Thing as his minions.

Used to be a time that every time I'd play in an IG game, Howard the Duck would carefully prepare his gauntlet, checking and re-checking the gems, then march forth.
Buuuuut tomorrow's the last IG game where I play and I decided, y'know what? Howard's gonna chance it without his fancy glove.
He's trapped in a world he doesn't belong in, verily.

Stingray with the Gauntlet for days, you guys...

I am wanting to use it on Parallax.

I paint my gauntlet white and pretend whoever I put it on is Michael Jackson.

Clixers, hide you Billy Batsons and Molly Hayes...

And power pack.

I've used it 3x thus far:

Skrull Ms. Marvel ----> 1200 point Skrull team that was a multi-player special scenario.
Fire Demon ---> So. Much. Fun. Got to Ultimate Godhood
Red Skull Chase ----> had 18 points left, so just threw it on for fun.

So I haven't used it much, and don't really have an 'IG-assignment-formula'.

I've run it on M.O.D.O.K. at a kill and keep event. THAT Was fun. But admittedly probably one of the best 200 points you can spend in the game.

I prefer to not put it on power pieces. I want to put it on John Constantine. Just because he's enough of an jerk to use it. I also think it would be alot of fun to pop it on Mary Jane Watson. Just to leave her alone in the back. Then eventually just get her to godhood. That or JJJ.

Hide yo kids, hide yo wives......

Bit late... But it's the thought that counts.

I like putting them on any of my Ms. Marvels for their lack of sufficient power. Especially Chaos War.

I've put the IG on Vet. Superman (Icons), and dear Lord it was beautiful.

I've but the gauntlet on my Throg to great effect as well as CR 105 superman which was insult to injury at one point. But i would like to throw a full gauntlet on 100pt dark phoenix dc 52 death stroke as well as super man from that set as well as flash but more importantly i really wanna throw it on Hawkeye from CW