i use it in my dark fusion deck, whenever my opponent tries to kill my black skull dragons or skull knights, i just flip Deck Devastation virus. It's also good with giant orc.

Once Deck Destruction Virus of Death comes out virus decks will be amazing. With both. No monsters for my opponent! hahah

DDV is possibly one of the most under-rated new cards in the set. If you run a few high attack dark monsters, it's deffiantely worth it. If they're ever put at risk of dying, DDV is like a "go out wiht a bang" card. Yesterday, in tournament play, I used it on my vampire lord, my opponent had 4 cards in hand and 1 set monster, I activate it, it destroys his f/d Cyber Jar, and then takes out his ENTIRE hand of Apprentice Magician, Magician of faith, and 2 Marauding captains. Obviously, it won the game for me. Also, it's helped me countless times knowing what to expect and adapt what I do to that, or in killing scape goats. Deffinately worth playing if you're playing the right deck type, and atleast side it against pheonix chaos. It kills almost every support card in that deck.

Here's a list of stuff it kills -

DD Warrior Lady
Magician of Faith
Apprentice Magician
Marauding Captain
Mystic Swordsman Level 2
Silent Swordsman level 3
Marauding Captain
Command Knight
Sangan
Anything Sangan Can search for
Cyber Jar
Scape Goats
Mataza
Spirit Reaper
Pyramid Turtle
Don Zaloog
Any Searcher

And that's just a few, but I was only listing commonly seen cards. As you can see, it takes out A LOT of problem cards.

DDV works great for me. hit an opponents cyber jar, they brought out 4 monsters killable by it, i got giant orc, terrorking, and something else. flipped DDV, sacrificed terrorking and took out their entire field and half their hand.