The weird thing is, despite the dearth of Silver Age and Bronze Age comics I've read, I swear I've read at least one of each of these hero-villain pairings.

Before becoming a world-conquering time-traveling nogoodnik, what was Per Degaton's job description?

--wyld

He was a laboratory assistant, washing test tubes like a good fellow.

And it is for this reason that I have an irrational fear of lab assistants, to this day.

Your question, Custom.

--wyld

In the original 1940s stories, what villain battled Doctor Fate more often than any other?

Wotan?

--wyld

No; while Wotan fought Doctor Fate three times in the 1940s, someone else fought him more than that.

Was it Weather Wizard ?


Just kidding there.

Was it Negal (or Nergal, I forget the spelling) ???

No, that's not who it was.

Was it Bud Abbott or Lou Costello?

Mad Dog?

Nabu himself ?

Now up in my photo album!

That's right, ignore the game for the sake of self-promotion.

We're just glad you're not Peter North.

Who's ignoring the game? No one has yet given a correct answer to my question; namely, what villain fought Doctor Fate more times in the 1940s than any other?

Nope, that's not who it is. Karkull only fought Fate twice in the 40s.