Ok, I just learned the game through some playtesting with the two starter decks. But I have a few questions, hopefully someone can answe them.

First, Plot Twists. When can you play these during the turn? I know during combat, but can they be played any time during the turn??

Powers, when can these be activated? Any time as well? I know there are some powers that are self explanatory but many others are not.

No where in the rulebook that I can find explains these two instances.

Thanks for any answers.

Yes u can play plot twists whenever you want.

most powers can be activated whenever. some cards specify when they can be played

both answers are in the rulebook somewhere

Plot twists and activated powers may be used whenever you have priority.

This is not the same as "whenever you want".

Furthermore, some plot twists and activated abilities are restricted. For example, Destiny may only use her ability during the build phase, while Pyro can use his ability anytime.
Flying Kick may be played anytime, while Savage Beatdown can only be played on an attacker, thus limiting it to the combat phase.

Note that when I reference "anytime" or a specific time, you can still only do it if you have priority, as Zaxx mentioned. Basically, you just have to wait until it is your turn to do something, then you can do as much as you want, as long as it's legal.

Thanks to all of you for answering my questions. I did find the mention of when you can use plot twists in the rule book. Powers weren't as easily defined.

Thanks