A very noobish question here, but one part Despotellis' trait is little confusing and was asked at a venue I played at on Sunday. The trait says "Despotellis does not block line of fire..." so if a friendly character is adjacent to an opposing Despotellis, would that character be able to make ranged attacks against other non-adjacent opposing characters, or do they have to make an attack against Despotellis?

The character wouldn't be able to make a ranged attack. Not blocking line of fire doesn't change that you're adjacent to an opposing character.

But if Despotellis was 2 squares away with another opposing character behind him, you could attack that character because Despotellis wouldn't block the line of fire.

Okay, cool. Thank you for clearing that up for me, I don't know why that was so confusing for me.