I just want to know the biggest baddie in each set...

One that has the most commanding prescence when used in the game..

By presence do you mean "biggest target when played".

My take:
IC: Firelord
CT: Nightcrawler
XP: Taskmaster
HT: Nightwing/Bats
CJ: Despero/Deathstroke

Now, most of these folks don't make it onto my teams, but I know I target them first when playing against them.

My picks:
IC: F-lord
CT: Fuzzy blue elf
XP: Taskmaster/ Mystique
HT: Batman
CJ: D-iz-espero

I've always had good luck with Spiral.
U and V Catwoman have helped me win a few
Despero makes onto all of my teams, and after tonight, i think Amazo will if he doesn't.

Also, when I pull out V Doom and Red Skull, my buddy starts whining!